This project aims to identify the most and least effective elements in colorectal cancer screening promotion images, with a focus on ethnic minorities in the UK and individuals in India. By using a combination of interviews, survey ratings, and eye-tracking technology, we will assess existing CRC screening promotion images to understand which visual and messaging elements resonate best and which fall short. Insights from these evaluations will help us identify cultural, emotional, and cognitive factors that influence engagement and comprehension. This data will then be used to inform the creation of optimized CRC promotion images, leveraging graphic design and generative AI to develop culturally sensitive and visually impactful materials that can enhance screening uptake. The project ultimately seeks to create more inclusive and effective health communication strategies that address the unique needs of underserved populations.